Ioannis Xenarios manages the Swiss-Prot and Vital-IT group. He received a Ph.D in immunology at the Ludwig Institute of Cancer Research and the Institute of Biochemistry. He worked on the development of the Database of Interacting Proteins (DIP) under the supervision of Prof. David Eisenberg at the University of California Los Angeles. He then became the head of Translational Bioinformatics at Serono (now Merck Serono) where his group developed computational methodologies in the area of proteomics, microarray and genetics. Principal investigator in European project on systems biology (ENFIN), computational infrastructure resources provider (ICGR-SIB), and domain specific databases and data mining analysis and expertise (EuroDia). On a more Swiss level his group is involved in SystemsX.ch both as a computational resource (Systems Biology IT-SyBIT) and at the interface to enable data-analysis and system modeling.